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Ethel Mathiasen posted an update 5 years, 7 months ago
We also identified a group of small cells that were capable of vigorous proliferation in the same liver samples. Therefore, it is plausible that the abnormally large GFP-positive polygonal cells are derived from the fusion of endogenous hepatocytes exposed to retrorsine and bone marrow cells, whereas the very small polygonal cells are derived by…[Read more]
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Ethel Mathiasen posted an update 5 years, 7 months ago
The presently described culture SU 5416 system may be useful for regenerative medicine, but the primary importance will be as a tool to elucidate the progression of thyroid disease. Moreover, this phenomenon could be induced in vivo because it can be achieved without introducing foreign genes. However, as we have not confirmed full functional…[Read more]
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Ethel Mathiasen posted an update 5 years, 7 months ago
ATRIP has several functions in ATR signaling including stabilizing the ATR protein, targeting ATR to replication stress sites, and contributing to the interaction with the TOPBP1 protein. TOPBP1 binding to the ATR-ATRIP complex activates ATR by inducing an unknown SID 3712249 structural change within ATR that increases ATR substrate affinity. The…[Read more]
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Ethel Mathiasen posted an update 5 years, 7 months ago
ATRIP has several functions in ATR signaling including stabilizing the ATR protein, targeting ATR to replication stress sites, and contributing to the interaction with the TOPBP1 protein. TOPBP1 binding to the ATR-ATRIP complex activates ATR by inducing an unknown structural change within ATR that increases ATR substrate affinity. The mutations…[Read more]
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Ethel Mathiasen posted an update 5 years, 7 months ago
In addition, Otto and Silhavy described increased expression of Cpx-regulated genes upon 1 h contact of Escherichia coli with artificial surfaces as compared to Beraprost sodium planktonic cells maintained in suspension; surprisingly, this regulation was observed with stationary phase cells in contact with a hydrophobic surface only. Lately, Li…[Read more]
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Ethel Mathiasen posted an update 5 years, 8 months ago
ATRIP has several functions in ATR signaling including stabilizing the ATR protein, targeting ATR to replication stress sites, and contributing to the interaction with the TOPBP1 protein. TOPBP1 binding to the ATR-ATRIP YU142670 complex activates ATR by inducing an unknown structural change within ATR that increases ATR substrate affinity. The…[Read more]
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Ethel Mathiasen posted an update 5 years, 8 months ago
In addition, Otto and Silhavy described increased expression of Cpx-regulated genes upon 1 h contact of Escherichia coli with artificial surfaces as compared to planktonic cells maintained in suspension; surprisingly, this regulation was observed with stationary phase cells in contact with a hydrophobic surface only. Lately, Li and co-workers…[Read more]
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Ethel Mathiasen posted an update 5 years, 8 months ago
We also identified a group of small cells that were capable of vigorous proliferation in the same liver samples. Therefore, it is plausible that the abnormally large GFP-positive polygonal cells are derived from the fusion of endogenous hepatocytes exposed to retrorsine and bone marrow cells, whereas the very small polygonal cells are derived by…[Read more]
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Ethel Mathiasen posted an update 5 years, 8 months ago
We also identified a group of small cells that were capable of vigorous proliferation in the same liver samples. Therefore, it is plausible that the abnormally large GFP-positive polygonal cells are derived from the fusion of endogenous hepatocytes exposed to retrorsine and bone marrow cells, whereas the very small polygonal cells are derived by…[Read more]
-
Ethel Mathiasen posted an update 5 years, 8 months ago
ATRIP has several functions in ATR signaling including stabilizing the ATR protein, targeting ATR to replication stress sites, and contributing to the interaction with the TOPBP1 protein. TOPBP1 binding to the ATR-ATRIP complex activates ATR by inducing an unknown structural change within ATR that increases ATR substrate affinity. The mutations…[Read more]
-
Ethel Mathiasen posted an update 5 years, 8 months ago
We also identified a group of small cells that were capable of vigorous proliferation in the same liver samples. Therefore, it is plausible that the abnormally large GFP-positive polygonal cells are derived from the fusion of endogenous hepatocytes exposed to retrorsine and bone marrow cells, whereas the very small polygonal cells are derived by…[Read more]
-
Ethel Mathiasen posted an update 5 years, 8 months ago
We also identified a group of small cells that were capable of vigorous proliferation in the same liver samples. Therefore, it is plausible that the abnormally large GFP-positive polygonal cells are derived from the fusion of endogenous hepatocytes exposed to retrorsine and bone marrow cells, whereas the very small polygonal cells are derived by…[Read more]
-
Ethel Mathiasen posted an update 5 years, 8 months ago
The presently described culture system may be useful for regenerative medicine, but the primary importance will be as a tool to elucidate the progression of thyroid disease. Moreover, this phenomenon could be induced in vivo because it can be achieved without introducing foreign genes. However, as we have not confirmed full functional…[Read more]
-
Ethel Mathiasen posted an update 5 years, 8 months ago
In addition, Otto and Silhavy described increased expression of Cpx-regulated genes upon 1 h contact of Escherichia coli with artificial surfaces as compared to planktonic cells maintained in suspension; surprisingly, this regulation was observed with stationary phase cells in contact with a hydrophobic surface only. Lately, Li and co-workers…[Read more]
-
Ethel Mathiasen posted an update 5 years, 8 months ago
We also identified a group of small cells that were capable of vigorous proliferation in the same liver samples. Therefore, it is plausible that the abnormally large GFP-positive polygonal cells are derived from the fusion of endogenous hepatocytes exposed to retrorsine and bone marrow cells, whereas the very small polygonal cells are derived by…[Read more]
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Ethel Mathiasen posted an update 5 years, 8 months ago
The presently described culture system may be useful for RX 821002 hydrochloride regenerative medicine, but the primary importance will be as a tool to elucidate the progression of thyroid disease. Moreover, this phenomenon could be induced in vivo because it can be achieved without introducing foreign genes. However, as we have not confirmed full…[Read more]
-
Ethel Mathiasen posted an update 5 years, 8 months ago
The presently described culture system may be useful for regenerative medicine, but the primary importance will be as a tool to elucidate the progression of thyroid disease. Moreover, this phenomenon could be induced in vivo because it can be achieved without introducing foreign genes. However, as we have not confirmed full functional…[Read more]
-
Ethel Mathiasen posted an update 5 years, 8 months ago
We also identified a group of small cells that were capable of vigorous proliferation in the same liver samples. Therefore, it is plausible that the abnormally large GFP-positive polygonal cells are derived from the fusion of endogenous hepatocytes exposed to retrorsine and bone marrow cells, whereas the very small polygonal cells are derived by…[Read more]
-
Ethel Mathiasen posted an update 5 years, 8 months ago
We also identified a group of small cells that were capable of vigorous proliferation in the same liver samples. Therefore, it is plausible that the abnormally large GFP-positive polygonal cells are derived from the fusion of endogenous hepatocytes exposed to retrorsine and bone marrow cells, whereas the very small polygonal cells are derived by…[Read more]
-
Ethel Mathiasen posted an update 5 years, 8 months ago
ATRIP has several functions in ATR signaling including stabilizing the ATR protein, targeting ATR to replication stress sites, and contributing to the interaction with the TOPBP1 protein. TOPBP1 binding to the ATR-ATRIP complex activates ATR by inducing an unknown structural change within ATR that increases ATR substrate affinity. The mutations…[Read more]
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