The most popularly studied networks are probably the TRN and PPI. However functional modules in a network may still be dispersed and unconnected among each other, trying to find causal disturbances in a network has been a major goal of many computational biologists. For examples, our group have tried to develop algorithms to identify primary and…[Read more]

Oral cancer is the sixth most common cancer worldwide. In India, extensive tobacco usage in various forms makes it the leading type of cancer in males and third most common cancer in females. Also, prevalence of oral buccal mucosa cancer type is high in the Indian subcontinent. The treatment modalities of oral cancer are based on various factors…[Read more]

The ROI were analyzed for cell number in at least three non-consecutive sections per animal. As expected, multiple CHATimmunoreactive cells within the medial septum and the diagonal band were observed. Mice subjected to the fimbria-fornix transection and infused with PBS alone, were characterized by a 50% loss in the number of the CHAT-positive…[Read more]

These results suggest that vitamin E is able to promote higher CD4+ and CD8+ T cells both locally and systemically, which may lead to enhanced tumor protection. Numerous antioxidants have bee shown to have antitumor effects like vitamin E. For example, olive oil phenols have been shown to inhibit proliferation and promote apoptosis of leukemia,…[Read more]

Oral cancer is the sixth most common cancer worldwide. In India, extensive tobacco usage in various forms makes it the leading type of cancer in males and third most common cancer in females. Also, prevalence of oral buccal mucosa cancer type is high in the Indian subcontinent. The treatment modalities of oral cancer are based on various factors…[Read more]

The ROI were analyzed for cell number in at least three non-consecutive sections per animal. As expected, multiple CHATimmunoreactive cells within the medial septum and the diagonal band were observed. Mice subjected to the fimbria-fornix transection and infused with PBS alone, were characterized by a 50% loss in the number of the CHAT-positive…[Read more]

The results clearly showed that the inhibition effect of rs57137919A on ABCG1 promoter activity was more potent under LXR agonist stimulation in different cell lines, suggesting that the activation of the ABCG1 gene promoter driven by LXR agonist might be suppressed by the rs57137919A allele. It is widely accepted that oxysterols, as the ligands…[Read more]

The ROI were analyzed for cell number in at least three non-consecutive sections per animal. As expected, multiple CHATimmunoreactive cells within the medial septum and the diagonal band were observed. Mice subjected to the fimbria-fornix transection and infused with PBS alone, were characterized by a 50% loss in the number of the CHAT-positive…[Read more]

The ROI were analyzed for cell number in at least three non-consecutive sections per animal. As expected, multiple CHATimmunoreactive cells within the medial septum and the diagonal band were observed. Mice subjected to the fimbria-fornix transection and infused with PBS alone, were characterized by a 50% loss in the number of the CHAT-positive…[Read more]

Oral cancer is the sixth most common cancer worldwide. In India, extensive tobacco usage in various forms makes it the leading type of cancer in males and third most common cancer in females. Also, prevalence of oral buccal mucosa cancer type is high in the Indian subcontinent. The treatment modalities of oral cancer are based on various factors…[Read more]

The ROI were analyzed for cell number in at least three non-consecutive sections per animal. As expected, multiple CHATimmunoreactive cells within the medial septum and the diagonal band were observed. Mice subjected to the fimbria-fornix transection and infused with PBS alone, were characterized by a 50% loss in the number of the CHAT-positive…[Read more]

Oral cancer is the sixth most common cancer worldwide. In India, extensive tobacco usage in various forms makes it the leading type of cancer in males and third most common cancer in females. Also, prevalence of oral buccal mucosa cancer type is high in the Indian subcontinent. The treatment modalities of oral cancer are based on various factors…[Read more]

The ROI were analyzed for cell number in at least three non-consecutive sections per animal. As expected, multiple CHATimmunoreactive cells within the medial septum and the diagonal band were observed. Mice subjected to the fimbria-fornix transection and infused with PBS alone, were characterized by a 50% loss in the number of the CHAT-positive…[Read more]

These results suggest that vitamin E is able to promote higher CD4+ and CD8+ T cells both locally and systemically, which may lead to enhanced tumor protection. Numerous antioxidants have bee shown to have antitumor effects like vitamin E. For example, olive oil phenols have been shown to inhibit proliferation and promote apoptosis of leukemia,…[Read more]

These results suggest that vitamin E is able to promote higher CD4+ and CD8+ T cells both locally and systemically, which may lead to enhanced tumor protection. Numerous antioxidants have bee shown to have antitumor effects like vitamin E. For example, olive oil phenols have been shown to inhibit proliferation and promote apoptosis of leukemia,…[Read more]

Talsaclidine Moreover, the new definition of drug resistant epilepsy was failure of adequate trials of two tolerated and appropriately chosen and used AED schedules to achieve sustained seizure freedom. In all eligible studies, types of AEDs were also variable. Moreover, drug-response was defined as patients with no seizure for more than three…[Read more]

Moreover, the new definition of drug resistant epilepsy was failure of adequate trials of two tolerated and appropriately chosen and used AED schedules to achieve sustained seizure freedom. In all eligible studies, types of AEDs were also variable. Moreover, drug-response was defined as patients with no seizure for more than three times the…[Read more]

The meta-10-Cl-BBQ analysis is a powerful statistical tool to estimate the incidence and risk of those uncommon serious drug-related toxicities and this approach has been utilized to demonstrate an increased risk in treatment related mortality with bevacizumab and VEGFR-TKIs in previous researches. To the best of our knowledge, this is the first…[Read more]

Meanwhile, the potent anti-platelet activity of K-134 also make it a potential alternative agent for preventing secondary cerebral infarction because antiplatelet therapy for secondary stroke prevention has been proved to be beneficial in clinical trials. Moreover, a double-blind, randomized trial of cilostazol and aspirin demonstrated that…[Read more]

Moreover, the new definition of drug resistant epilepsy was failure of adequate trials of two tolerated and appropriately chosen and used AED schedules to achieve sustained seizure freedom. In all eligible studies, types of AEDs were also variable. Moreover, drug-response was defined as patients with no seizure for more than three times the…[Read more]