Elwin Chappell

  • Therefore, the decreased apoptosis revealed in the present study, associated with already published previous data that have shown the capacity of the adipose cells to produce cytokines and its plasticity, could lead to insights for further research that may explain the complete role of MAT in CD. Obesity is a metabolic disease characterized by…[Read more]

  • The most popularly studied networks are probably the TRN and PPI. However functional modules in a network may still be dispersed and unconnected among each other, trying to find causal disturbances in a network has been a major goal of many computational biologists. For examples, our group have tried to develop algorithms to identify primary and…[Read more]

  • In summary, we propose that in the AD brain, intraneuronal accumulation of Ab increases the vulnerability of neurons to subsequent chronic exposure to soluble Ab. This combined exposure to intra- and extracellular Ab leads to degenerative changes in neurons and apoptosis through a K + efflux mediated mechanism. Glioblastoma is a highly aggressive…[Read more]

  • In summary, we propose that in the AD brain, intraneuronal accumulation of Ab increases the vulnerability of neurons to subsequent chronic exposure to soluble Ab. This combined exposure to intra- and extracellular Ab leads to degenerative changes in neurons and apoptosis through a K + efflux mediated mechanism. Glioblastoma is a highly aggressive…[Read more]

  • The most popularly studied networks are probably the TRN and PPI. However functional modules in a network may still be dispersed and unconnected among each other, trying to find causal disturbances in a network has been a major goal of many computational biologists. For examples, our group have tried to develop algorithms to identify primary and…[Read more]

  • These studies revealed abnormalities in the MAT of CD patients, including the infiltration of macrophages and T cells, perivascular inflammation, fibrosis and differences in adipocytes number and size. There are currently no studies regarding apoptosis in the MAT of CD individuals, nor in the animal model of hypertrophied MAT with associated…[Read more]

  • The most popularly studied networks are probably the TRN and PPI. However functional modules in a network may still be dispersed and unconnected among each other, trying to find causal disturbances in a network has been a major goal of many computational biologists. For examples, our group have tried to develop algorithms to identify primary and…[Read more]

  • In summary, we propose that in the AD brain, intraneuronal accumulation of Ab increases the vulnerability of neurons to subsequent chronic exposure to soluble Ab. This combined exposure to intra- and extracellular Ab leads to degenerative changes in neurons and apoptosis through a K + efflux mediated mechanism. Glioblastoma is a highly aggressive…[Read more]

  • These studies revealed abnormalities in the MAT of CD patients, including the infiltration of macrophages and T cells, perivascular inflammation, fibrosis and differences in adipocytes number and size. There are currently no studies regarding apoptosis in the MAT of CD individuals, nor in the animal model of hypertrophied MAT with associated…[Read more]

  • In summary, we propose that in the AD brain, intraneuronal accumulation of Ab increases the vulnerability of neurons to subsequent chronic exposure to soluble Ab. This combined exposure to intra- and extracellular Ab leads to degenerative changes in neurons and apoptosis through a K + efflux mediated mechanism. Glioblastoma is a highly aggressive…[Read more]

  • In summary, we propose that in the AD brain, intraneuronal accumulation of Ab increases the vulnerability of neurons to subsequent chronic exposure to soluble Ab. This combined exposure to intra- and extracellular Ab leads to degenerative changes in neurons and apoptosis through a K + efflux mediated mechanism. Glioblastoma is a highly aggressive…[Read more]

  • These studies revealed abnormalities in the MAT of CD patients, including the infiltration of macrophages and T cells, perivascular inflammation, fibrosis and differences in adipocytes number and size. There are currently no studies regarding apoptosis in the MAT of CD individuals, nor in the animal model of hypertrophied MAT with associated…[Read more]

  • The most popularly studied networks are probably the TRN and PPI. However functional modules in a network may still be dispersed and unconnected among each other, trying to find causal disturbances in a network has been a major goal of many computational biologists. For examples, our group have tried to develop algorithms to identify primary and…[Read more]

  • Therefore, the decreased apoptosis revealed in the present study, associated with already published previous data that have shown the capacity of the adipose cells to produce cytokines and its plasticity, could lead to insights for further research that may explain the complete role of MAT in CD. Obesity is a metabolic disease characterized by…[Read more]

  • Therefore, the decreased apoptosis revealed in the present study, associated with already published previous data that have shown the capacity of the adipose cells to produce cytokines and its plasticity, could lead to insights for further research that may explain the complete role of MAT in CD. Obesity is a metabolic disease characterized by…[Read more]

  • The most popularly studied networks are probably the TRN and PPI. However functional modules in a network may still be dispersed and unconnected among each other, trying to find causal disturbances in a network has been a major goal of many computational biologists. For examples, our group have tried to develop algorithms to identify primary and…[Read more]

  • The most popularly studied networks are probably the TRN and PPI. However functional modules in a network may still be dispersed and unconnected among each other, trying to find causal disturbances in a network has been a major goal of many computational biologists. For examples, our group have tried to develop algorithms to identify primary and…[Read more]

  • In summary, we propose that in the AD brain, intraneuronal accumulation of Ab increases the vulnerability of neurons to subsequent chronic exposure to soluble Ab. This combined exposure to intra- and extracellular Ab leads to degenerative changes in neurons and apoptosis through a K + efflux mediated mechanism. Glioblastoma is a highly aggressive…[Read more]

  • In summary, we propose that in the AD brain, intraneuronal accumulation of Ab increases the vulnerability of neurons to subsequent chronic exposure to soluble Ab. This combined exposure to intra- and extracellular Ab leads to degenerative changes in neurons and apoptosis through a K + efflux mediated mechanism. Glioblastoma is a highly aggressive…[Read more]

  • The most popularly studied networks are probably the TRN and PPI. However functional modules in a network may still be dispersed and unconnected among each other, trying to find causal disturbances in a network has been a major goal of many computational biologists. For examples, our group have tried to develop algorithms to identify primary and…[Read more]

  • Load More