Itis, superinfected with MDR Gram-negative bacilli, requiring adapted salvage antibiotic therapy and surgical decompression. Instances two, three 4/2014: suspected cases, females (39, 51, 57 year-old), painless red-vesicular lesion and black eschar on fingers, surrounding edema, right after get in touch with with equivalent lesions on animals. All had constructive B. anthracis in-house serology. Case 5/2015: a 43 year-old shepherd with meningo-encephalitis: fever, psycho-motor agitation, hemiparesis, aphasia, neck-stiffness, CSF compatible with acute bacterial meningitis; black eschars on each hands. From CSF and MedChemExpress GDC-0994 cutaneous lesions, DNA-Bacillus anthracis was good PCR-techniques performed in Victor Babe Clinical Hospital, Bucharest, exactly where the patient was transferred in ICU). scan/nsw074 Situations 6,7,eight 9/July 2016: two confirmed, 2 probable, all shepherds with deceased animals, all cutaneous forms: a cluster of 3 (2 men along with a lady: 67, 42 and 61 year-old) in addition to a 34 year-old man. All sufferers had favorable evolution. Conclusions There’s a vital enhance in anthrax cases in south-eastern Romania, all in animal-breeders, connected with an inappropriate veterinary surveillance. Not all cutaneous forms had a rapid good evolution, a single created prospective fatal complications. The anthrax meningo-encephalitis described here had an unexpected favorable outcome, probable due to the young age, good prior health, early suspicion and prompt treatment. Consent Written informed consent was obtained from the individuals for publication of this Case report and any accompanying photos. A copy from the written consent is available for overview by the Editor of this journal.A102 Understanding, threat perception and attitudes of healthcare workers in the National Institute for Infectious Diseases “Prof. Dr. Matei Bal” with regards to Ebola Daniela Piigoi1,2, Teodora Ionescu3, Oana Sndulescu1,two, Maria Niescu1,two, Bogdan Niescu1, Iulia Monica Musta4, Sorina Claudia Boldeanu4, Florentina Furtunescu1, Adrian Streinu-Cercel1,2 1 Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; 2 National Institute for Infectious Diseases “Prof. Dr. Matei Bal”, Bucharest, Romania; 3Infection Control Department, National Institute of Endocrinology “C. I. Parhon”, Bucharest, Romania; 4Public Well being Authority, Bucharest, Romania Correspondence: Daniela Piigoi ([email protected]) BMC Infectious Ailments 2016, 16(Suppl 4):A102 Background The outbreak of Ebola virus illness (EVD) in 2014 has exerted a terrific stress on healthcare systems each inside, but also outside the African continent, inside the try cdev.12038 to recognize and manage imported cases in an effort to avert further transmission. In Romania, the National Institute for Infectious Illnesses “Prof. Dr. Matei Bal” was the designated health-related facility to handle doable instances of EVD. Our study aims to evaluate the information, attitudes and danger perception in the Institute’s healthcare workers (HCWs) relating to Ebola virus disease and the recent epidemic. Solutions We designed a cross-sectional survey based on a self-administered printed questionnaire comprised of 26 concerns. In June 2016, all healthcare physicians and nurses had been invited to take aspect voluntarily and anonymously in the study. Data have been analyzed making use of Microsoft Excel (2013) and IBM SPSS Statistics (v. 22). Outcomes Questionnaires have been filled out by 157 HCWs. Physicians represent 36 of all respondents. All participants are familiar with Ebola virus disease, but only 54 of nurses had discovered about it just before th.