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The following variables had been analysed with respect to survival: hospital, age, gender, place, no of lymph nodes and lymph node ratio (LNR), T stage, and TNM stage. Survival curves had been estimated by the Kaplan eier process [7] and compared using the logrank test [8]. Numerous prognostic variables had been analysed together with the Cox proportional hazards model [9] utilizing the SPSS 17 package.Material and solutions Individuals from a national cohort have been operated in 2000, and follow-up was until December 2007, a imply of 7.five years later. Three teaching neighborhood hospitals, Haraldsplass Deaconal Hospital, Stavanger University Hospital, and Akershus University Hospital contributed individuals. Surgery All three hospitals are teaching community hospitals, and also the individuals were operated with an open access by a large number of surgeons. At that time, added radical surgery was unusual, and it is actually fair to assume that radical surgery generally constituted a moderate mesocolic resection. If metastases had been diagnosed, individuals and tumor conditions have been assessed concerning feasibility for resection. Follow-up Sufferers normally went towards the outpatient clinic each third month for the very first 2 years and after that each and every sixth month till 5 years had passed. Blood tests with carcinoembryonic antigen measurement and ultrasonography in the liver and chest X-ray were carried out. Elderly sufferers are stead-bound as well as if a handful of of them were not followed up often, they could be tracked and life status ascertained via their identity number in the official National Population Registry. Death certificates for all deceased individuals had been obtainable via Statistics, Norway.Final results Two hundred sixty-nine individuals, 152 (56.five ) ladies and 117 guys, with a imply age of 71 years (range, 203 years) were studied. Certainly one of the hospitals operated male sufferers that have been younger, with a mean of 67 years.Int J Colorectal Dis (2011) 26:1299Surgery The various tumor areas are shown in Table 1. Tumor locations were not unique between the hospitals (p=0.059). Right hemicolectomy and sigmoid resection have been essentially the most widespread procedures (78.four ). Locoregional R0 resections to get a single tumor place had been carried out in 264 individuals, while double resections (n=4) along with a suspected locoregional R1 resection (n=1) were completed in 5 sufferers. Pathology There had been no significant differences between hospitals relating to TNM stage distribution: 34 sufferers (12.six ) had been stage I, 116 sufferers (43.1 ) had been stage II, 93 individuals (34.six ) were stage III, and 26 individuals (9.six ) had been stage IV. The number of lymph nodes harvested for several stages were 8.7 (stage I), ten.3 (stage II), ten.9 (stage III), and 10.3 (stage IV). In 11 sufferers, the pathologist had Title Loaded From File classified the T category and TNM stage but omitted to specify the number of lymph nodes present. The imply quantity in 258 sufferers was ten.3 lymph nodes per specimen. Twelve or additional lymph nodes were examined in 41.1 (106/258) of the resected specimens. Drastically fewer lymph nodes (p0.001) were harvested at certainly one of the hospitals. Otherwise, the 3 patient populations had similar qualities. Survival analysis General in-hospital mortality was five.2 (14/269; range, four.36.3 ). Urgent surgery had a mortality of 12.5 (3/24), whereas the electiv.