Foundation Grant CMMI-0954283 along with a seed grant awarded by the 11-Deoxojervine mechanism of action Healthcare Technique Institute and Children’s Healthcare of Atlanta. Dr. Swann was also supported by the Harold R. and Mary Anne Nash Junior Faculty Endowment Fund. Received: 21 August 2014 Accepted: 10 JuneReferences 1. Penchansky R, Thomas JW. The concept of access: definition and partnership to consumer satisfaction. Med Care. 1981;19(two):127?0. 2. Khan AA. An integrated strategy to measuring potential spatial access to healthcare services. Socio Econ Program Sci. 1992;26(4):275?7. 3. Khan AA, Bhardwaj SM. Access to healthcare – a conceptual framework and its relevance to healthcare arranging. Eval Well being Prof. 1994;17(1):60?6. four. Beck JR. Optimized resource-allocation in medicine applying network flows. Med Decis Mak. 1984;4(four):532. 5. da Silva MEM, Santos ER, Borenstein D. Implementing regulation policy in Brazilian Health Care Regulation Centers. Med Decis Mak. 2010;30(three):366?9. 6. Parkan C, Hollands L. The usage of efficiency jir.2011.0094 linear applications for sensitivity analysis in healthcare decision-making. Med Decis Mak. 1990;10(2):116?five. 7. Luo W, Wang FH. Measures of spatial accessibility to well being care inside a GIS environment: synthesis and also a case study inside the Chicago region. Environ Plann B-Plann Des. 2003;30(six):865?4. eight. Luo W, Qi Y. An enhanced two-step floating catchment location (E2SFCA) method for measuring spatial accessibility to main care physicians. Wellness Place. 2009;15(four):1100?. 9. Delamater PL. Spatial accessibility in suboptimally configured health care systems: A modified two-step floating catchment region (M2SFCA) metric. Well being Spot. 2013;24:30?three. ten. Wan N, Zou B, Sternberg T. A three-step floating catchment location method for analyzing spatial access to health services. Int J Geogr Inf Sci. 2012;26(six):1073?9. 11. Griffin PM, Scherrer CR, Swann JL. Optimization of neighborhood overall health center areas and service offerings with statistical have to have estimation. IIE Trans. 2008;40(9):880?2. 12. Daskin MS, Dean LK. Location of Wellness Care Facilities. In: Sainfort MB F, Pierskalla W, editors. Handbook of OR/MS in Health Care: A Handbook of Strategies and Applications. 2004. p. 43?6. 13. Schweikhart SB, Smithdaniels VL. Place and service mix choices for any managed health-care network. Socio Econ Program Sci. 1993;27(4):289?02.Li et al. BMC Well being Services Research (2015) 15:Web page 13 of14. Alejo JS, Martin MG, Ortega-Mier M, Garcia-Sanchez A. Mixed integer programming model for optimizing the layout of an ICU automobile. BMC Health Serv Res. 2009;9:224. 15. Begur SV, Miller DM, Weaver JR. An integrated spatial DSS for scheduling and routing home-health-care nurses. Interfaces. 1997;27(four):35?eight. 16. Deo S, Iravani S, Jiang TT, Smilowitz K, Samuelson S. Improving overall health outcomes by means of improved capacity allocation inside a community-based chronic care model. Oper Res. 2013;61(6):1277?four. 17. Rosenhead J. Community-based operations research: decision modeling for regional impact and diverse populations. Interfaces. 2013;43(six):609?0. 18. Ekici A, Keskinocak P, Swann JL. Pandemic influenza response: food distribution logistics. Manuf Serv Oper Handle. 2014;16(1):11?7.